Table 3.
Univariate and Multivariable Logistic Regression Analysis of the Association of AFP Levels With Maximum Tumor Diameter in cm.
| Variable | Size |
P value | OR (95% CI) (univariate) | OR (95% CI, P value) (multivariate) | |
|---|---|---|---|---|---|
| <5 cm n = 88 | >5 cm n = 420 | ||||
| Gender | 0.8321 | NA | |||
| Male | 72 (81.8%) | 372 (88.6%) | Ref | ||
| Female | 16 (18.2%) | 48 (11.4%) | 1.72 (0.93–3.20) | ||
| Age | 0.0061 | ||||
| ≤40 | 4 (4.5%) | 71 (16.9%) | 4.27 (1.52–12.03) | 3.99 (1.41–11.29,P = 0.009) | |
| >40 | 84 (95.5%) | 349 (83.1%) | Ref | ||
| Etiology | 0.9321 | NA | |||
| HBHC | 53 (60.2%) | 255 (60.7%) | Ref | ||
| NBNC | 35 (39.8%) | 165 (39.3%) | 1.02 (0.64–1.63) | ||
| AFP (ng/ml) Mean ± SD | 58660.60 ± 240108.55 | 70650.01 ± 224775.15 | <0.0012 | NA | |
| AFP(ng/ml) | O.0011 | ||||
| <10 | 26 (29.5%) | 66 (15.7%) | Ref | ||
| 10–400 | 30 (34.1%) | 116 (27.6%) | 1.84 (0.59–5.64) | 1.51 (0.82–2.79,P = 0.185) | |
| >400 | 32 (36.4%) | 238 (56.7%) | 2.06 (0.73–5.76) | 2.79 (1.55–5.05,P = 0.001) | |
| AFP(ng/ml) | 0.0011 | ||||
| ≤400 | 56 (63.6%) | 182 (43.3%) | Ref | ||
| >400 | 32 (36.4%) | 238 (56.7%) | 2.29 (1.42–3.68) | 2.19 (1.36–3.54,P = 0.001) | |
All values: Means ± Standard Deviation as continuous; Frequencies and percentage (%) as categorical.
1.Chi-square test 2.Mann–Whitney U test.
MTD (Maximum tumor diameter); AFP (Alfa-fetoprotein); HBHC (Hepatitis B and hepatitis C); NBNC (Nonhepatitis B and nonhepatitis C).