Table 4.
Univariate and Multivariable Logistic Regression Analysis of the Association of AFP Levels With Pathological Grade of Tumor.
| Variable | Pathological grade |
P value | OR (95% CI) [univariate] | OR (95% CI, P value) [multivariate] | |
|---|---|---|---|---|---|
| Well/moderate n = 98 | Poor/undifferentiated n = 40 | ||||
| Gender | 0.9671 | NA | |||
| Female | 10 (12.8%) | 5 (14.3%) | Ref | ||
| Male | 68 (87.2%) | 30 (85.7%) | 0.98 (0.32–2.98) | ||
| Age | 0.801 | NA | |||
| ≤40 | 16 (20.5%) | 6 (17.1%) | Ref | ||
| >40 | 62 (79.5%) | 29 (82.9%) | 0.88 (0.34–2.30) | ||
| Etiology | 0.111 | NA | |||
| NBNC | 49 (50%) | 14 (35%) | Ref | ||
| HBHC | 49 (50%) | 26 (65%) | 1.86 (0.87–3.98) | ||
| AFP (ng/ml) Mean ± SD | 50088.98 ± 213031.23 | 68513.40 ± 169304.82 | 0.0722 | NA | |
| AFP(ng/ml) | O.2891 | ||||
| <10 | 31 (31.6%) | 7 (17.5%) | Ref | ||
| 10–400 | 29 (29.6%) | 12 (30%) | 1.84 (0.63–5.29) | NA | |
| >400 | 38 (38.8%) | 21 (52.5%) | 2.44 (0.92–6.51) | NA | |
| AFP(ng/ml) | 0.1411 | NA | |||
| ≤400 | 60 (61.2%) | 19 (47.5%) | Ref | ||
| >400 | 38 (38.8%) | 21 (52.5%) | 1.75 (0.83–3.66) | ||
| MTD (cm) | 0.5711 | NA | |||
| ≤5 | 16 (16.3%) | 5 (12.5%) | Ref | ||
| >5 | 82 (83.7%) | 35 (87.5%) | 1.37 (0.46–4.02) | ||
All values: Mean ± Standard Deviation as continuous; Frequencies and percentage (%) as categorical.
1.Chi-square test 2.Mann–Whitney U test.
MTD (Maximum tumor diameter); AFP (Alfa-fetoprotein); HBHC (Hepatitis B and hepatitis C); NBNC (Nonhepatitis B and nonhepatitis C).