Table 2.

Comparison of clinicopathologic features by post-operative exocrine replacement.

	Post-operative Pancreatic Exocrine Insufficiency
	No	Yes	P
	(n = 76)	(n = 6)
Median Age (IQR)	46 (35–60)	47 (44–53)	0.80
Gender			0.62
Male	38	2
Female	38	4
Median BMI (IQR)	29 (25–33)	30 (22–40)	0.78
Underlying Diagnosis			0.13
Sporadic	36	1
MEN1	19	1
VHL	21	4
VHL v Non-VHL			0.046
Non-VHL	55	2
VHL	21	4
Familial v Sporadic			0.15
Sporadic	55	2
Familial	21	4
Cystic Pancreas			0.60
No	58	4
Yes	18	2
Functional Tumor			0.05
No	32	5
Yes	44	1
History of Pancreatitis			0.62
No	73	6
Yes	3	0
History of Alcohol Abuse			0.47
No	69	6
Yes	6	0
History of Smoking			0.12
No	53	6
Yes	22	0
Pre-Op Diabetes			0.34
No	66	6
Yes	10	0
Surgical Procedure			< 0.001
Enucleation	37	2
Distal Pancreatectomy	36	1
Pancreatiocoduodenectomy	3	3
Volume of Pancreas Resected			0.30
Mean (Range)	31 cm3 (0.02–397 cm3)	55 cm3 (5–119 cm3)
Median (IQR)	10 cm3 (2–52 cm3)	47 cm3 (44–66 cm3)
Multifocal			0.48
No	49	3
Yes	27	3
Tumor Grade			0.86
Grade 1	40	3
Grade 2	19	2
Grade 3	2	0
Metastasis			0.18
No	66	4
Yes	10	2
Cysts in remnant pancreas			0.32
No	63	4
Yes	13	2
PNET in remnant pancreas			0.45
No	52	5
Yes	24	1
New or Worsening Diabetes			0.73
No	67	5
Yes	9	1
Median Length of Days Follow Up (IQR)	571 (12–1784)	2503(581–3025)	0.11