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. Author manuscript; available in PMC: 2022 Jun 6.
Published in final edited form as: J Mol Biol. 2020 Nov 19;433(2):166718. doi: 10.1016/j.jmb.2020.11.017

Fig. 3.

Fig. 3.

Identifying sites in M1-9 that affect HIV-2 genome packaging. A. Effects of mutations in the first four (M1234) or last five (M56789) sites on HIV-2 RNA packaging. B. Effects of mutating sites 1,2, and 4 (M124) or site 3 (M3) on HIV-2 RNA packaging. Results shown are averages of at least three independent experiments. Error bars, standard deviations; open circles indicate values obtained from each independent experiment. P-values were calculated by one-way ANOVA with Bonferroni correction for multiple pairwise comparisons; n.s., not significant; ****, p-value < 0.0001.