Table 3.

Comparison of plasma concentrations of cytokines, chemokines and growth factors between newly diagnosed breast cancer patients and control subjects.

	Breast Cancer (n=98)			Controls (n=45)			p value
Chemokines	Median pg/mL	95% LCL of Median	95% UCL of Median	Median pg/mL	95% LCL of Median	95% UCL of Median
CXCL5 ENA 78	535,58	250,70	763,49	2246,51	1540,24	3246,49	0,000
CCL26 Eotaxin 3	4,31	4,31	8,41	6,36	3,28	8,41	0,354
CX3CL1 Fraktalkine	445,13	399,04	489,30	397,12	366,07	431,69	0,009
CCL5 RANTES	84,22	78,32	90,09	48,72	36,30	66,96	0,000
CXCL10 IP-10	485,82	426,98	607,59	543,33	498,35	638,22	0,868
CXCL9 MIG	91,31	76,65	112,33	92,92	74,64	117,50	0,399
CCL23 MIP-3	949,97	701,29	1136,60	1476,91	1267,40	1860,61	0,049
Cytokines	Median pg/mL	95% LCL of Median	95% UCL of Median	Median pg/mL	95% LCL of Median	95% UCL of Median	p value
IL-2	9,01	8,19	10,37	9,81	7,29	11,50	0,329
IL-4	126,24	102,57	156,37	146,78	113,16	200,93	0,187
IL-6	10,52	8,90	11,30	10,40	7,56	13,71	0,749
IL-8	9,61	8,18	10,87	9,81	7,49	10,34	0,204
IL-16	1931,86	1569,84	2087,37	3535,39	2932,85	3813,73	0,000
Interferon α2	174,28	152,73	192,52	199,64	176,29	214,94	0,008
IL-1 Ra	418,74	346,33	466,68	503,33	448,08	625,49	0,018
Interferon γ	59,74	51,01	66,56	69,55	44,35	80,45	0,086
IL-10	42,76	36,50	50,87	47,61	34,16	59,25	0,406
IL-17A	23,05	20,19	25,90	23,92	20,84	23,38	0,961
TGF β1	20353,26	14180,32	24904,45	23785,83	16184,42	36390,72	0,986
Growth Factors	Median pg/mL	95% LCL of Median	95% UCL of Median	Median pg/mL	95% LCL of Median	95% UCL of Median	p value
FGF-21	24,36	8,64	33,80	8,64	8,64	8,64	0,001
GDF-15	806,82	741,37	879,48	430,03	368,72	467,45	0,000
M-CSF	84,41	65,74	88,98	13,34	13,34	13,34	0,000
GM-CSF	13,30	13,30	13,30	13,30	13,30	13,30	1,000
G-CSF	8,75	8,75	8,75	8,75	8,75	8,75	1,000
VEGF	9,14	2,40	13,64	8,66	2,87	13,64	0,566