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. 2022 May 23;10:902571. doi: 10.3389/fped.2022.902571

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Copyright © 2022 Yang, Xing, Tan and Zhang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Article hypothesis and ideas. BA may be an immune-related disease mediated by viral infection, toxic injury, and genetics, or even an autoimmune disease. Inherent and specific immunity play an important role in the occurrence and development of BA. DE-IGs in BA livers, normal livers, and hepatitis B livers were analyzed, and the proportion of 22 immune cells in all samples of the dataset was predicted using CIBERSORT software to elucidate the pathogenesis of BA.