Figure 3.

(A) Transplantation-free survival estimates by baseline hemodynamics from the catheterization performed at the time of pulmonary hypertension diagnosis. Mean pulmonary artery pressure (PAPm) (n = 634) and PAPm/mean systemic arterial pressure (SAPm) ratio (n = 467) are associated with risk of the composite of death/lung transplantation (P ⩽ 0.001). Patients in the highest tertile have the highest hazard of death/lung transplantation, and patients in the middle tertile have significantly higher risk compared with those in the lowest tertile. The figures are truncated at 15 years; some follow-up extended past 20 years, but no events occurred after 15 years. (B) Survival estimates by baseline hemodynamics from the catheterization performed at the time of pulmonary hypertension diagnosis, according to competing-risks analysis. PAPm (n = 634, P = 0.029) and PAPm/SAPm ratio (n = 467, P = 0.001) are associated with mortality. Patients in the highest tertile for PAPm (>50 mm Hg) have a higher hazard of death than those with PAPm in the first tertile, but patients in the middle tertile cannot be shown to differ from either adjacent tertile. For PAPm/SAPm, patients in the highest tertile have the highest hazard of death/lung transplantation. The figures are truncated at 15 years; some follow-up extended past 20 years, but no events occurred after 15 years. Cath =  catheterization.