TABLE 1.
Basic information of hub genes
| Hub genes | Related description | Degree | Value difference | Trend |
|---|---|---|---|---|
| JUN | Jun Proto‐Oncogene | 12 | 3.63 | Up‐regulate |
| FOS | Fos Proto‐Oncogene | 8 | 1.49 | Up‐regulate |
| PTGS2 | Prostaglandin‐Endoperoxide Synthase 2 | 5 | 2.70 | Up‐regulate |
| NR4A2 | Nuclear Receptor Subfamily 4 Group A Member 2 | 4 | 2.89 | Up‐regulate |
| TNFAIP3 | TNF Alpha Induced Protein 3 | 4 | 2.89 | Up‐regulate |
The expressions of JUN, FOS, PTGS2, NR4A2, and TNFAIP3 in the peripheral blood of gout patients were all higher than those of healthy controls.