FIGURE 6.

Correlation of ACE2 expression with immune infiltration level in BRCA (TIMER). (A) ACE2 expression is significantly negatively correlated to tumor purity and has significant positive correlations with infiltrating levels of B cells, CD8⁺ T cells, CD4⁺ T cells, neutrophils, and dendritic cells in BRCA, but not with that of macrophages. (B) Copy number mutation of ACE2 in BRCA could partly inhibit the immune infiltration level of CD8⁺ T cells, CD4⁺ T cells, neutrophils, macrophages, and dendritic cells, but not of B cells (p‐value Significant Codes: 0 ≤ *** <0.01 ≤ * <0.05≤. <0.1)