Table 1.
Clinical and biological characteristics according to TyG index tertiles
| Characteristics | T1 (5.48–7.17) (n = 244) | T2 (7.18–7.76) (n = 244) | T3 (7.7–10.82) (n = 243) | P-value |
|---|---|---|---|---|
| Age (years) | 64 (59, 69) | 64 (58, 68) | 63 (56, 67) | 0.062 |
| Sex (M/F) | 1.32 | 1.57 | 1.38 | 0.634 |
| SBP (mmHg) | 140 (128, 156) | 141 (129, 159) | 140 (125, 156) | 0.805 |
| DBP (mmHg) | 82 (76, 92) | 83 (76, 90) | 83 (76, 93) | 0.750 |
| BMI (kg/m2) | 25.72 (23.65, 29.01) | 26.67 (23.94, 29.33) | 27.47 (24.61, 29.67) | < 0.001 |
| Drinking | 86 (35.2%) | 90 (36.9%) | 77 (31.7%) | 0.468 |
| Smoking | 120 (49.2%) | 124 (50.8%) | 119 (50.0%) | 0.905 |
| TC (mg/dL) | 4.27 (3.56, 5.04) | 4.49 (3.91, 5.28) | 5.04 (4.36, 6.00) | < 0.001 |
| TG (mg/dL) | 1.04 (0.84, 1.19) | 1.58 (1.30, 1.96) | 2.52 (1.87, 3.33) | < 0.001 |
| HDL-C (mg/dL) | 1.16 (0.97, 1.37) | 1.05 (0.89, 1.22) | 0.99 (0.80, 1.16) | < 0.001 |
| LDL-C (mg/dL) | 2.57 (1.99, 3.22) | 2.74 (2.19, 3.31) | 2.89 (2.30, 3.62) | < 0.001 |
| FPG (mmol/L) | 5.63 (5.09, 6.18) | 6.31 (5.58, 7.60) | 9.30 (7.01, 12.48) | < 0.001 |
| HbA1c (%) | 5.8 (5.5, 6.2) | 6.1 (5.7, 6.8) | 6.9 (6.0, 8.4) | < 0.001 |
| TyG index | 6.88 (6.65, 7.04) | 7.42 (7.30, 7.60) | 8.17 (7.94, 8.49) | < 0.001 |
| Glucose metabolism state | ||||
| NGR | 59 (24.2%) | 26 (10.7%) | 8 (3.3%) | < 0.001 |
| Pre-DM | 131 (53.7%) | 97 (39.8%) | 37 (15.2%) | |
| DM | 54 (22.1%) | 121 (50.8%) | 198 (81.5%) | |
| Number of vessels with stenosis | ||||
| 1 | 105 (43.0%) | 94 (38.5%) | 61 (25.1%) | < 0.001 |
| ≥ 2 | 139 (57.0%) | 150 (61.5%) | 182 (74.9%) | |
| Degree of coronary stenosis | ||||
| 50% ≤ CS < 70% | 76 (31.1%) | 65 (26.6%) | 45 (18.5%) | 0.005 |
| CS ≥ 70% | 168 (68.9%) | 179 (73.4%) | 198 (81.5%) | |
Data are presented as median (interquartile range) or number (proportion, %)
M, male; F, female; TyG, triglyceride glucose; SBP, systolic blood pressure; DBP, diastolic blood pressure; BMI, body mass index; FPG, fasting plasma glucose; HbA1c, glycated haemoglobin; TC, total cholesterol; TG, triglycerides; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; NGR, normal glucose regulation; Pre-DM, prediabetes mellitus; DM, diabetes mellitus; CS, coronary stenoses