Table 2.
Clinical and biological characteristics according to CAD severity
| Characteristics | Total (n = 731) | Single-vessel CAD (n = 260) | Multi-vessel CAD (n = 471) | P-value |
|---|---|---|---|---|
| Age (years) | 63 (58, 68) | 63 (57, 68) | 63 (58, 69) | 0.361 |
| Sex (M/F) | 1.42 | 1.10 | 1.65 | 0.009 |
| SBP (mmHg) | 140 (127, 156) | 140 (126, 154) | 141 (127, 156) | 0.225 |
| DBP (mmHg) | 83 (76, 91) | 83 (76, 90) | 83 (76, 91) | 0.944 |
| BMI (kg/m2) | 26.67 ± 3.90 | 26.47 ± 3.75 | 26.86 ± 3.91 | 0.077 |
| Drinking | 253 (34.6%) | 91 (35.0%) | 162 (34.4%) | 0.506 |
| Smoking | 363 (49.7%) | 123 (47.3%) | 240 (51.0%) | 0.084 |
| TC (mg/dL) | 4.61 (3.87, 5.43) | 4.45 (3.78, 5.21) | 4.69 (3.92, 5.63) | 0.018 |
| TG (mg/dL) | 1.51 (1.11, 2.17) | 1.42 (1.05, 2.04) | 1.57 (1.14, 2.21) | 0.018 |
| HDL-C (mg/dL) | 1.05 (0.88, 1.24) | 1.10 (0.92, 1.32) | 1.03 (0.87, 1.21) | 0.002 |
| LDL-C (mg/dL) | 2.72 (2.14, 3.39) | 2.63 (2.02, 3.20) | 2.80 (2.19, 3.50) | 0.002 |
| FPG (mmol/L) | 6.44 (5.53, 8.66) | 5.98 (5.28, 7.34) | 6.71 (5.66, 9.40) | < 0.001 |
| HbA1c (%) | 6.1 (5.6, 7.0) | 6.0 (5.5, 6.5) | 6.2 (5.7, 7.3) | < 0.001 |
| TyG index | 7.42 (7.04, 7.94) | 7.32 (6.93, 7.75) | 7.52 (7.10, 8.06) | < 0.001 |
| Glucose metabolism state | ||||
| NGR | 93 (12.7%) | 45 (17.3%) | 48 (10.2%) | < 0.001 |
| Pre-DM | 265 (36.3%) | 113 (43.5%) | 152 (32.3%) | |
| DM | 373 (51.0%) | 102 (39.2%) | 271 (57.5%) | |
| Drug therapy | ||||
| Antihypertensive | 545 (74.6%) | 196 (75.4%) | 349 (74.1%) | 0.461 |
| Antilipidemic | 561 (76.7%) | 198 (76.2%) | 363 (77.1%) | 0.518 |
| Antiplatelet | 708 (96.9%) | 246 (94.6%) | 462 (98.1%) | 0.010 |
Data are presented as mean ± standard deviation or median (interquartile range) or number (proportion, %)
M, male; F, female; TyG, triglyceride glucose; SBP, systolic blood pressure; DBP, diastolic blood pressure; BMI, body mass index; FPG, fasting plasma glucose; HbA1c, glycated haemoglobin; TC, total cholesterol; TG, triglycerides; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; NGR, normal glucose regulation; Pre-DM, prediabetes mellitus; DM, diabetes mellitus