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. 2022 Jun 6;21:96. doi: 10.1186/s12933-022-01523-7

Table 3.

Associations between CAD severity and risk factors

Variables Multi-vessel coronary artery disease
OR (95% CI) β P-value
Sex
 Female Reference
 Male 0.666 (0.490–0.905) − 0.406 0.009
Age 1.009 (0.989–1.029) 0.009 0.389
Smoking
 No Reference
 Yes 1.307 (0.965–1.770) 0.267 0.084
Drinking
 No Reference
 Yes 1.114 (0.810–1.531) 0.108 0.506
SBP 1.004 (0.997–1.012) − 0.004 0.186
DBP 1.000 (0.988–1.012) − 0.075 0.987
BMI 1.036 (0.996–1.077) 0.035 0.077
TC 1.182 (1.040–1.343) 0.237 0.010
TG 1.065 (0.946–1.199) 0.063 0.297
HDL-C 0.405 (0.233–0.704) − 0.903 0.130
LDL-C 1.328 (1.121–1.573) 0.284 0.001
FPG 1.148 (1.084–1.217) 0.138  < 0.001
HbA1c 1.356 (1.191–1.544) 0.304  < 0.001
TyG index 1.715 (1.349–2.179) 0.539  < 0.001

Compared with single-vessel CAD

OR, odds ratios; CI, confidence interval; β, regression coefficient; TyG, triglyceride glucose; TC, total cholesterol; TG, triglycerides; HDL-C, high-density lipoprotein cholesterol; LDL-C, low-density lipoprotein cholesterol; FPG, fasting plasma glucose; HbA1c, glycated haemoglobin