Table 5.

Associations between TyG index and CAD severity according to different glucose metabolism states

Glucose regulation state	Variables	Multi-vessel coronary artery disease
Glucose regulation state	Variables	OR (95% CI)^a	P-value	OR (95% CI)^b	P-value	OR (95% CI)^c	P-value
NGR	TyG index	1.828 (0.802–4.166)	0.151	1.747 (0.726–4.203)	0.213	1.797 (0.706–4.573)	0.219
	T1	Reference		Reference		Reference
	T2	1.292 (0.512–3.257)	0.588	1.227 (0.458–3.287)	0.684	1.329 (0.467–3.783)	0.594
	T3	3.321 (0.619–17.820)	0.161	3.052 (0.529–17.608)	0.212	3.373 (0.545–25.628)	0.180
Pre-DM	TyG index	0.990 (0.623–1.574)	0.966	1.055 (0.658–1.691)	0.824	0.926 (0.565–1.517)	0.182
	T1	Reference		Reference		Reference
	T2	0.918 (0.540–1.562)	0.753	0.945 (0.553–1.616)	0.837	0.868 (0.449–1.509)	0.759
	T3	0.825 (0.396–1.719)	0.608	0.905 (0.430–1.908)	0.794	0.791 (0.367–1.707)	0.616
DM	TyG index	1.646 (1.127–2.404)	0.010	1.721 (1.170–2.532)	0.006	1.717 (1.161–2.539)	0.007
	T1	Reference		Reference		Reference
	T2	1.191 (0.610 -2.327)	0.609	1.192 (0.609–2.334)	0.608	1.030 (0.513–2.069)	0.933
	T3	2.185 (1.142–4.181)	0.018	2.273 (1.180–4.376)	0.014	2.105 (1.069–4.144)	0.031

Compared with single-vessel CAD

OR, odds ratios; CI, confidence interval; NGR, normal glucose regulation; Pre-DM, prediabetes mellitus; DM, diabetes mellitus

^aModel 1: unadjusted

^bModel 2: adjusted for age and sex;

^cModel 3: adjusted for age, sex, SBP, DBP, BMI, smoking, drinking, and antihypertensive, antilipidemic, and antiplatelet drug therapy