Table 3.

Spearman correlations of AGEs and the different isoforms of sRAGE isoforms with age in healthy controls (CTR) and patients with type 2 diabetes

		CTR (n = 156)	Type 2 diabetes (n = 362)
sRAGE	Correlation coefficient	− 0.161	− 0.052
	P-value	0.073	0.323
esRAGE	Correlation coefficient	0.042	− 0.051
	P-value	0.646	0.330
cRAGE	Correlation coefficient	− 0.261**	− 0.020
	P-value	0.003	0.711
AGEs	Correlation coefficient	0.069	0.028
	P-value	0.446	0.600
AGEs/sRAGE	Correlation coefficient	0.195*	0.025
	P-value	0.032	0.631
AGEs/esRAGE	Correlation coefficient	0.035	0.081
	P-value	0.701	0.123
AGEs/cRAGE	Correlation coefficient	0.246**	0.014
	P-value	0.006	0.796

^**p < 0.01 for Spearman’s regression. Significant correlations are in bold