Table 4.
Age- and HbA1c-adjusted multiple quantile regression model for the evaluation of AGEs and sRAGE isoforms in type 2 diabetes complications
Neuropathy | Nephropathy | Retinopathy | PAD | MACE | ||||||
---|---|---|---|---|---|---|---|---|---|---|
Variable | Coeff. | p | Coeff. | p | Coeff. | p | Coeff. | p | Coeff. | p |
sRAGE | − 130.7 | 0.041 | 2.130 | 0.976 | 44.7 | 0.456 | 26.4 | 0.786 | − 9.875 | 0.889 |
cRAGE | − 30.40 | 0.475 | 28.49 | 0.551 | 85.38 | 0.034 | 127.9 | 0.049 | − 81.14 | 0.087 |
AGEs | 3.187 | 0.158 | − 0.487 | 0.847 | − 5.965 | 0.005 | − 0.863 | 0.801 | − 1.23 | 0.466 |
AGEs/sRAGE | 0.010 | 0.008 | 0.001 | 0.846 | − 0.009 | 0.016 | − 0.005 | 0.349 | − 0.001 | 0.794 |
AGEs/esRAGE | 0.020 | 0.038 | − 0.001 | 0.960 | − 0.005 | 0.579 | 0.007 | 0.642 | − 0.023 | 0.028 |
AGEs/cRAGE | 0.016 | 0.090 | 0.005 | 0.656 | − 0.024 | 0.006 | − 0.013 | 0.363 | 0.001 | 0.912 |
In bold significant associations
Quantile regression models the relationship between a set of predictor variables (type 2 diabetes complications) and specific quantiles of target variables
Coefficient are displayed for the 0.5 quantile (median)