Table 6.
The rate of missed diagnosis of ROP, sensitivity and specificity according to the different screening criteria
| Screening Criteria | Infants Missed With Mild ROP, N (%) | Infants Missed With Severe ROP, N (%) | Total Infants Missed With ROP, N (%) | Sensitivity (%) | Specificity (%) | Positive predictive value (%) | Negative predictive value (%) |
|---|---|---|---|---|---|---|---|
| China Screening Guideline (BW < 2000 g or GA < 32w) | 54 (7.42) | 2 (0.27) | 56 (7.69) | 92.3 | 98.3 | 92.30 | 98.32 |
| USA Screening Guideline (BW < 1500 g or GA < 30w) | 183 (25.14) | 5 (0.69) | 188 (25.82) | 74.2 | 93.9 | 72.58 | 94.35 |
| UK Screening Guideline (BW ≤ 1500 g or GA < 32w) | 101 (13.87) | 3 (0.41) | 104 (14.29) | 85.2 | 96.9 | 85.64 | 96.77 |
| BW ≤ 2000 g or GA ≤ 30w | 65 (8.93) | 3 (0.41) | 68 (9.34) | 90.7 | 98.0 | 90.66 | 97.96 |
| BW ≤ 1750 g or GA ≤ 32w | 86 (11.81) | 2 (0.27) | 88 (12.09) | 87.9 | 97.4 | 87.91 | 97.37 |
| BW ≤ 1750 g or GA ≤ 30w | 134 (18.41) | 4 (0.55) | 138 (18.96) | 81.0 | 99.6 | 98.01 | 96.02 |
| BW ≤ 2100 g or GA ≤ 33w | 34 (4.67) | 1 (0.14) | 35 (4.81) | 96.3 | 98.7 | 94.29 | 98.95 |