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. 2022 Jun 6;2022(6):CD003645. doi: 10.1002/14651858.CD003645.pub4

Kornecki 2001.

Study characteristics
Methods Cross‐over RCT of prone and supine positions
Participants Included: 10 children aged 8 weeks to 16 years who required mechanical ventilation for moderate to severe acute respiratory failure
Excluded: not stated
Mean age: 5 years; mean weight: 22.5 kg; diagnosis: sepsis/acute respiratory distress syndrome (4), pneumonia (3), other (3)
Setting: 36‐bed paediatric critical care unit in a tertiary care university‐based children's hospital in the USA
Interventions Supine first, then random order of first study position; 12 hours in each position
Outcomes Oxygenation index
Data collected at 2, 4, 6, 8, 12 hours for each position
Notes Heart rate, PaCO2 and arterial BP were not reported
The study was supported by the Department of Critical Care Medicine, Division of Respiratory Medicine, Hospital for Sick Children, University of Toronto, Toronto, Ontario.
Risk of bias
Bias Authors' judgement Support for judgement
Random sequence generation (selection bias) Unclear risk Not stated
Allocation concealment (selection bias) Unclear risk Not stated
Blinding of outcome assessment (detection bias)
All outcomes Unclear risk Not stated
Incomplete outcome data (attrition bias)
All outcomes Unclear risk Loss to follow‐up: 2/12 patients were not enrolled because they could not be placed in prone position due to physical restrictions