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. 2022 Jun 6;2022(6):CD011574. doi: 10.1002/14651858.CD011574.pub2

Lurie 2020.

Methods RCT
Participants Setting: multicentre across 8 outpatient physiotherapy clinics in the USA.
N = 66 in the PD subgroup
Sample: recruited from patients referred for physiotherapy for gait and/or balance problems at participating clinics.
Age: not reported for the PD group.
Inclusion criteria (PD group): aged 65 years or older; one of the following fall risk factors, timed up and go ≥ 8 seconds, Dynamic Gait Index ≤ 22/24, Berg BalancecScale < 54/56.
Exclusion criteria: primary problem positional vertigo; not able to undertake intervention due to severe physical limitations
Disease severity at baseline: not reported
Interventions Exercise
1. Exercise: surface perturbation treadmill training plus multi‐modal balance training. For the perturbation training, participants wore a harness and practised responding to perturbations (forwards, backwards and occasionally sideways) using the ActiveStep system. Multimodal balance training included strength, flexibility and balance exercise, gait training and education. Participants attended a supervised session around 2 to 3 times per week for 4 to 6 weeks, approximately 45 minutes per session with 15 minutes of this perturbation training, plus home unsupervised sessions 4 to 5 times per week. 
2. Exercise: multi‐modal balance training alone, including strength, flexibility and balance exercise, gait training and education. Participants attended a supervised session around 2 to 3 times per week for 4 to 6 weeks, approximately 45 minutes per session, plus home unsupervised sessions 4 to 5 times per week. 
Outcomes 1. Number of fallers
Other outcomes reported but not included in this review
Notes At randomisation, 34 participants were in the perturbation group and 32 in the standard care group.
At 3 months there was data for 24 participants in the perturbation group and 25 in the standard care group.
Participants having any fall at 3 months: 9 (37%) perturbation group; 8 (32%) standard care group.
Fall data collected using a fall diary and 3‐monthly telephone calls for 12 months.
Funding source: Agency for Healthcare Research and Quality