ACTRN12618001515280.

Study name	SAFE‐PD ‐ Stepping to Avoid Fall Events in Parkinson’s disease
Methods	RCT
Participants	Target sample size: 44 Inclusion criteria: diagnosed with Parkinson’s disease (according to UK PD Society Brain Bank Criteria); stable on anti‐Parkinsonian medications for at least 1 month; Living independently in the community or retirement village; able to communicate in English language. Exclusion criteria: Hoehn & Yahr stage >3; diagnosis of other neurological and/or significant cognitive impairments (Montreal Cognitive Assessment (MOCA) < 19); atypical Parkinsonism; inability to stand or walk 30 m without assistance; less than 6 months post deep brain stimulation surgery; medical conditions which would preclude physical assessment or training using perturbation (e.g. duodopa); history of weekly (12+) falls in past 3 months.
Interventions	1. Volitional and reactive step training using "home‐based exergames" for 80+ minutes per week (3 or 4 sessions per week) for 12 weeks. Participants will also visit the research laboratory to undertake three individual sessions (one per month, 120 minutes in total) with each session focusing on balance recovery progressively from 1) slips, 2) trips and 3) mix of trips and slips. 2. Control: Usual activities
Outcomes	1. Rate of falls Other outcomes not relevant to this review
Starting date	September 11, 2018
Contact information	Prof Stephen Lord, Neuroscience Research Australia, Email: s.lord@neura.edu.au
Notes