NCT04874051.

Study name	Sensor‐based assessment and rehabilitation of Balance in Neurological Diseases (BALANCE)
Methods	RCT
Participants	Target sample size: 120 overall, with a subset of these with Parkinson's disease Inclusion criteria for participants with Parkinson's disease: Berg Balance Scale < 50/56, able to stand without support for 1 minute, Functional Independence measure < 100/126, Barthel Index < 80/100, Hoehn and Yahr stage 1.5 to 3, Subitem "freezing" when walking"of the UPDRS ≤ 2. Exclusion criteria: untreated epilepsy, major depressive disorder, fractures, dementia, ideomotor apraxia, neglect, severe impairment of verbal comprehension, severe acoustic and visual disorders.
Interventions	1. Balance exercise using exercise in a virtual reality environment, 60 minutes, 5 times per week for 3 weeks 2. Balance exercise without the virtual reality environment, 60 minutes, 5 times per week for 3 weeks
Outcomes	1. Rate of falls Other outcomes not relevant to this review
Starting date	September 2, 2019
Contact information	Dr Andrea Turolla San Camillo IRCCS Email: andrea.turolla@ospedalesancamillo.net
Notes