Interactions between key residues of BRD7/BRD9 and three inhibitors (all values are in kcal mol⁻¹).

BRDs	Key residues	Inhibitors
		4L2			5U6			6KT
		Sidechain	Backbone	Total	Sidechain	Backbone	Total	Sidechain	Backbone	Total
BRD7	A154	−0.25	−0.17	−0.42	−0.33	−0.29	−0.62	−0.02	−0.02	−0.04
	F155	−1.40	−0.23	−1.63	−2.07	−0.01	−2.08	−0.62	−0.12	−0.74
	F156	−0.46	−0.15	−0.61	−0.64	−0.16	−0.81	−0.48	−0.10	−0.58
	F158	−0.51	0.03	−0.48	−0.44	0.15	−0.29	−0.03	0.03	−0.01
	V160	−1.89	−0.24	−2.13	−1.88	−0.42	−2.30	−0.78	−0.04	−0.82
	I164	−1.18	−0.10	−1.28	−2.18	−0.23	−2.41	−0.61	−0.14	−0.75
	Y168	−0.31	−0.01	−0.33	−0.29	−0.02	−0.31	−0.34	−0.01	−0.35
	N211	−1.86	0.02	−1.84	−1.86	0.02	−1.84	−1.34	0.01	−1.33
	Y217	−2.41	−0.14	−2.55	−2.63	−0.15	−2.78	−1.33	−0.09	−1.42
BRD9	G43	−0.11	−0.07	−0.18	−0.15	−0.37	−0.52	−0.01	−0.05	−0.06
	F44	−1.51	−0.30	−1.81	−2.09	−0.21	−2.31	−1.17	−0.19	−1.37
	F45	−0.40	−0.13	−0.53	−0.58	−0.16	−0.74	−0.64	−0.11	−0.74
	F47	−0.57	0.06	−0.51	−0.57	0.24	−0.34	−0.04	0.04	0.00
	V49	−1.93	−0.25	−2.19	−2.02	−0.46	−2.48	−1.04	−0.05	−1.09
	I53	−1.24	−0.09	−1.33	−2.24	−0.20	−2.44	−0.67	−0.14	−0.81
	A54	−0.47	−0.08	−0.54	−0.60	−0.20	−0.81	−0.43	−0.06	−0.49
	Y57	−0.28	−0.01	−0.30	−0.29	−0.01	−0.31	−0.94	−0.01	−0.96
	A96	−0.33	−0.31	−0.64	−0.35	−0.22	−0.57	−0.45	−0.35	−0.80
	Y99	−0.48	−0.02	−0.50	−0.51	−0.02	−0.52	−0.49	−0.05	−0.54
	N100	−1.80	0.01	−1.79	−1.82	0.01	−1.81	−1.32	−0.00	−1.32
	Y106	−2.37	−0.14	−2.51	−2.62	−0.13	−2.76	−1.46	−0.11	−1.57