. Author manuscript; available in PMC: 2023 Jan 1.

Published in final edited form as: J Neural Transm (Vienna). 2021 Dec 29;129(1):95–103. doi: 10.1007/s00702-021-02455-4

Table 1.

Comparison of bipolar disorder cases and control group.

Characteristic	BD (n = 15)	Control (n = 15)	p
Age (years), mean (SD)^a	65.8 (13.8)	63.0 (11.6)	0.50
Female, n (%)^b	11 (73.3)	11 (73.3)	1.00
BMI (kg/m²), mean (SD)^a	24.2 (5.4)	24.1 (5.9)	0.81
Ethnicity, n (%)^b
White/mixed	10 (66.6)	8 (53.3)
Black	5 (33.3)	7 (46.6)	0.58
Cognitive impairment, n (%)^b	2 (13.4)	0 (100.0)	0.48
NPI total score, mean (SD)^a	54.8 (33.1)	1.0 (2.4)	0.0001
PMI (hours), mean (SD)^a	13.9 (2.52)	15.7 (5.0)	0.20
Current alcohol use, n (%)^b	7 (46.6)	6 (40.0)	1.00
Hypertension, n (%)^b	8 (53.3)	9 (60.0)	1.00
Diabetes mellitus, n (%)^b	6 (40.0)	2 (13.3)	0.21
Coronary artery disease, n (%)^b	4 (26.6)	4 (26.6)	1.00
TDP-43 (pg/mL), mean (SD)^a	865.7 (177.8)	617.9 (211.9)	0.004

BD bipolar disorder; SD standard deviation; BMI body mass index; NPI neuropsychiatric inventory; PMI postmortem interval; TDP-43 TAR DNA-binding protein 43; N number of cases %: percentage; CDR cognitive dementia rating

Mann–Whitney test

Fisher exact test