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. Author manuscript; available in PMC: 2022 Jun 6.
Published in final edited form as: J Leukoc Biol. 2021 May 11;109(6):1033–1043. doi: 10.1002/JLB.1HI1120-779R

FIGURE 2. Declining blood neutrophil numbers despite elevated plasma G-CSF levels were observed in elderly rhesus macaques.

FIGURE 2.

(A) Blood neutrophil counts in 142 animals aged 3 – 26 years old were examined by nonparametric Spearman correlation. (B) Blood neutrophil counts and medians with interquartile range were plotted and compared between age groups of rhesus macaques by Kruskal-Wallis test followed by Dunn’s post-test for pairwise comparisons. (C) Plasma G-CSF levels (pg/ml) were measured in 132 samples from 126 rhesus macaques as well as 12 specimens collected from six animals at different ages. Results were analyzed by nonparametric Spearman correlation. (D) G-CSF levels in age groups of rhesus macaques were plotted along with medians with interquartile ranges and compared by Kruskal-Wallis test with Dunn’s post-test for pairwise comparisons. *, P < 0.05; **, P < 0.01; ***, P < 0.001. P < 0.05 was considered statistically significant.