Fig. 3.

Biomarker correlations. Blood cell populations, plasma viral loads (VL), and cytokines measured at the imaging time points were correlated with (A and B) spleen, (C and D) lung, and (E and F) bone marrow DPA-714 Vt values. Positive and negative correlations with P < 0.01 are shown in dark green and red bars, respectively. The black bars indicate correlations that have a P > 0.01. Pearson partial correlations accounting for repeated measures were used to calculate the correlation coefficients and the P values. Plasma VL and cytokine values were log-transformed before performing the correlations in order to achieve a more normal distribution. Log-transformations were not needed for platelet counts, WBC counts, and differential.