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. 2022 Jun 6;17(6):e0268532. doi: 10.1371/journal.pone.0268532

Table 2. Cox proportional hazard regression analysis for number of days a patient received oxygen supplementation.

Parameter Multivariate analysis
HR (95% CI) p valuea
Age
 0–<3 months - 0.001
 3–6 months 3.76 (1.75–8.11)
 6–<12 months 2.94 (1.37–6.29)
 12–<48 months 3.81 (1.78–8.13)
Gender
 Female - 0.976
 Male 1.01 (0.62–1.65)
Underlying risk
 No - 0.202
 Yes 1.61 (0.79–3.31)
Length of symptoms at intercept
 ≤3 days - 0.389
 >3 days 0.78 (0.44–1.37)
PES3-total score (3 items; 1-unit increase) 0.86 (0.75–0.99) 0.029

N = 72, 2 patients were excluded as they did not have PES score on day 1 available. 1 patient was excluded due to missing age.

ap value was calculated by a likelihood ratio test.

A global chi-square test for the proportional hazard assumption showed no deviation (p = 0.447). A graphical review of possible time-dependent coefficients over time (plots of residuals for individual predictors) showed no deviation from the proportional hazard assumption.

Abbreviations: CI–Confidence Interval, HR–Hazard Ratio, PES–Physical Examination Scoring