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Identification of the duper allele. (A) Filtering process to identify candidate variants of duper alleles. One high-putative impact variant (Cry1) and 3 moderate-putative impact variants remained after the filtering process. (B) The p.Pro193fs mutation in Cry1 was predicted to cause an early stop codon in the CRY1 protein in duper. (C) Sanger sequencing validation of the 1bp deletion in duper.
