Table 2. Minimum inhibitory concentration (MIC) (µg/ml) of Mycobacterium abscessus (Mab) clinical isolates +/-penicillin-binding protein and hypothetical lipoprotein (PBP-lipo) knockdown (cell wall antibiotics).
Ampicillin | Amoxicillin | ||||
---|---|---|---|---|---|
Clinical isolate | -ATc | +ATc | -ATc | +ATc | |
ATCC 19977 | >256 | 2 | >256 | 2 | |
T35 | >256 | <0.5 | >256 | <0.5 | |
T37 | >256 | <0.5 | >256 | <0.5 | |
T49 | >256 | 4 | >256 | 4 | |
T50 | >256 | 4 | >256 | 4 | |
T51 | >256 | 2 | >256 | 2 | |
T53 | >256 | 4 | >256 | 2 | |
T56 | >256 | <0.5 | >256 | <0.5 | |
BWH-B | >256 | 8 | >256 | 2 | |
BWH-C | >256 | 4 | >256 | 8 | |
BWH-E | >256 | 4 | >256 | 2 |