Table 3. Minimum inhibitory concentration (MIC) (µg/ml) of Mycobacterium abscessus (Mab) clinical isolates +/-penicillin-binding protein and hypothetical lipoprotein (PBP-lipo) knockdown (rifampicin and clarithromycin).
| Rifampicin | Clarithromycin | ||||
|---|---|---|---|---|---|
| Clinical isolate | -ATc | +ATc | -ATc | +ATc | |
| ATCC 19977 | 32 | 2 | 16 | 0.125 | |
| T35 | 4 | 0.25 | 2 | 0.25 | |
| T37 | 16 | 1 | 2 | 0.25 | |
| T49 | 64 | 4 | 2 | 0.25 | |
| T50 | 32 | 1 | 16 | 0.25 | |
| T51 | 64 | 4 | 16 | 0.5 | |
| T53 | 32 | 1 | 8 | 0.5 | |
| T56 | 8 | 1 | 2 | 0.25 | |
| BWH-B | 32 | 1 | 16 | 0.25 | |
| BWH-C | 32 | 2 | 32 | 1 | |
| BWH-E | 16 | 1 | 16 | 0.125 | |