Table 1.
Characteristic | LVNC (n = 20) | Controls (n = 20) | P |
---|---|---|---|
Age [years] | 46 (33–57) | 54 (43–57) | 0.16 |
Female sex | 9 (45%) | 7 (35%) | 0.52 |
Body mass index [kg/m2] | 24.3 ± 4.0 | 26.2 ± 4.6 | 0.09 |
Heart rate [bpm] | 65.5 ± 11.6 | 64.8 ± 13.1 | 0.6 |
Systolic blood pressure [mmHg] | 117 ± 13.4 | 131 ± 9.7 | 0.03 |
Diastolic blood pressure [mmHg] | 71.0 ± 8.5 | 78.6 ± 8.8 | 0.07 |
NYHA class: | |||
Class I | 17 (85%) | 20 (100%) | |
Class II | 3 (15%) | 0 (0%) | |
Left ventricular ejection fraction (CMR) [%] | 51.6 ± 8.6 | 62.0 ± 4.3 | < 0.0001 |
Medication: | |||
Acetylsalicylic acid | 1 (5%) | 0 (0%) | |
Phenprocoumon | 3 (15%) | 0 (0%) | |
Beta-blocker | 5 (25%) | 0 (0%) | |
ACEI or ARB | 8 (40%) | 0 (0%) | |
Diuretics | 6 (30%) | 0 (0%) |
Data are shown as mean ± standard deviation or median (interquartile range) or number (percentage). ACEI — angiotensin-converting enzyme inhibitor; ARB — angiotensin-receptor blocker; CMR — cardiac magnetic resonance imaging; LVNC — left ventricular non-compaction cardiomyopathy; NYHA — New York Heart Association