Table 3.
Univariate Cox analysis showing the association between the number of myocardial inflammatory infiltrates and poor clinical outcome after 2-year and 5-year follow-up.
Cardiac inflammatory infiltration and endothelial activation markers [cells/mm2] | HR (95% CI) | |||
---|---|---|---|---|
| ||||
2-year follow-up | P | 5-year follow-up | P | |
CD3+ | 1.085 (1.04–1.132) | < 0.001 | 1.061 (1.02–1.103) | 0.003 |
CD45ro+ | 1.079 (1.025–1.136) | 0.004 | 1.048 (0.998–1.101) | 0.06 |
CD68+ | 1.075 (0.862–1.34) | 0.523 | 1.029 (0.867–1.223) | 0.74 |
CD4+− | 1.01 (0.91–1.13) | 0.82 | 1.013 (0.908–0.13) | 0.82 |
CD54+ | 0.82 (0.53–1.25) | 0.35 | 0.816 (0.532–1.254) | 0.35 |
HLA-DR+ | 1.02 (0.91–1.14) | 0.7 | 1.022 (0.915–1.143) | 0.7 |
CD3+ ≥ 13 cells/mm2 | 4.481 (1.588–12.64) | 0.005 | 2.181 (1.009–4.711) | 0.047 |
CD45ro+ ≥ 11.5 cells/mm2 | 5.261 (1.854–14.93) | 0.002 | 2.892 (1.217–6.871) | 0.016 |
Values are expressed as hazard ratio (HR) and 95% confidence interval (CI). Significant at the p-value of < 0.05 (bold value).