TABLE 2.
Lean mass of infants at 3, 6, and 12 mo in response to 1000 compared with 400 IU/d of supplemental vitamin D, post hoc ANCOVA1
| Lean mass, g | 1000 IU/d minus 400 IU/d | 400 IU/d minus Reference | 1000 IU/d minus Reference | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Time point | Reference | 400 IU/d | 1000 IU/d | Difference (95% CI) | P value | Difference (95% CI) | P value | Difference (95% CI) | P value |
| 3 mo | 4327.0 ± 682.7 | 4225.1 ± 640.0 | 4326.3 ± 534.9 | 170.6 (−174.0, 515.1) | 0.47 | −252.3 (−624.7, 120.1) | 0.25 | −81.7 (−454.3, 290.8) | 0.86 |
| 6 mo | 5010.5 ± 754.0 | 4975.4 ± 608.9 | 5062.2 ± 707.4 | 161.5 (−193.3, 516.2) | 0.53 | −199.6 (−579.3, 180.1) | 0.43 | −38.2 (−415.4, −339.1) | 0.97 |
| 12 mo | 6715.1 ± 784.6 | 6690.4 ± 1121.7 | 7012.5 ± 904.6 | 389.3 (−1.8, 776.7) | 0.0486 | −162.1 (−573.8, 249.6) | 0.62 | 227.2 (−167.8, 622.1) | 0.37 |
1
Data were tested using a linear mixed-effects model for lean mass (g) as the primary outcome. Infant (ID) modeled as a random effect, followed by post hoc Tukey's tests with Tukey-Kramer adjustment for multiple comparisons. Adjusted for sex, skin tone, parity, maternal prepregnancy BMI, parental age at delivery, and family income.