Table 1.

Glucocorticoid Therapy Options After Surgery for CS

Medication	Initial Total Daily Dose	Tapering Increment	Comments
Hydrocortisone	30–60 mg/day	5–10 mg/day	Shift to circadian rhythm in 2–6 weeks
Prednisone	10–20 mg/day	1–2 mg/day	Pro-drug, unreliable
Prednisolone	10–20 mg/day	1–2 mg/day
Methylprednisolone	8–16 mg/day	1–2 mg/day
Dexamethasone	2–5 mg/day	0.25–0.5 mg/day	Difficult to titrate once daily dose < 1 mg/day
Fludrocortisone acetate	0.1–0.4 mg/day	0.05–0.1 mg/day	Only after BLA

BLA, bilateral adrenalectomy