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. 2022 Jun 6;13:3130. doi: 10.1038/s41467-022-30868-6

Fig. 1. Acute effects of PRATA on blood pressure and peripheral vasomotion.

Fig. 1

a Surgical diagram of PRATA. b Acute changes of the intracarotid arterial MAP post PRATA, n = 6 per group; Data are mean ± SEM. **P < 0.01, ***P < 0.001, ****P < 0.0001. Analysis of variance (ANOVA), Bonferroni post-hoc test, two-sided. c–f Changes of intracarotid arterial MAP post unilateral and half-volume PRATA (c), pararenal adipose tissue ablation (d), epididymal adipose tissue ablation (e) and inguinal adipose tissue ablation (f), n = 6 per group; Data are mean ± SEM. P > 0.05. ANOVA, Bonferroni post-hoc test, two-sided. g–l Laser speckle contrast imaging of the blood flow of mesenteric artery (g), carotid artery (h) and renal cortex (i), and quantification (j–l). n = 5 per group for all the imaging of the blood flow experiments in (j) and (l). n = 7 for WKY-PRATA group, n = 5 for SHR-PRATA group in (k). Data are mean ± SEM. *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.0001. ANOVA, Bonferroni post-hoc test, two-sided.