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. 2022 Jun 6;8:62. doi: 10.1038/s41378-022-00386-y

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 8 — a A rectangular cross-sectional multiline separation structure¹⁶⁶. b Spiral VEM channel to suggest that the Dean drag force and viscoelastic forces together alter the trajectory in a spiral channel¹⁶⁷. c Particles traveling in between the sample and sheath flow¹⁶⁹. d Co-flow of viscoelastic and Newtonian media devices, which achieves an over 90% separation efficiency and purity of 1 µm Staphylococcus aureus and 2–3 µm platelets¹⁷⁰