Skip to main content
. 2022 May 28;19(5):343–353. doi: 10.11909/j.issn.1671-5411.2022.05.010

Table 2. Predictors of unscheduled rehospitalization and all-cause death (univariate analysis).

Variables Death
(n = 15)
Survivals (n = 153) P-value HR [95% CI] P-value Rehosp. (+)
(n = 41)
Rehosp. (-)
(n = 123)
P-value HR [95% CI] P-value
Data are presented as mean ± SD or n (%). *NA: due to the small number of observations. ACS: acute coronary syndrome; AF: atrial fibrillation; BMI: body mass index; CABG: coronary artery bypass grafting; CHF: congestive heart failure; CKD: chronic kidney disease; COPD: chronic obstructive pulmonary disease; EF: ejection fraction; Hgb: hemoglobin; MI: myocardial infarction; NSTEMI: non-ST-segment elevation myocardial infarction; PCI: percutaneous coronary intervention; STEMI: ST-segment elevation myocardial infarction; TIA: transient ischemic attack; UA: unstable angina.
Female 10 (66.7%) 66 (43.1%) 0.081 2.40 [0.82; 7.03] 0.109 22 (53.7%) 50 (40.6%) 0.146 1.48 [0.80; 2.73] 0.213
Age, yrs 78.7 ± 7.7 74.2 ± 7.3 0.022 1.07 [1.01; 1.14] 0.025 78.4 ± 8.2 73.4 ± 6.7 < 0.001 1.08 [1.04; 1.12] < 0.001
BMI, kg/m2 25.0 ± 3.8 27.0 ± 4.5 0.098 0.90 [0.79; 1.02] 0.097 26.0 ± 3.3 27.1 ± 4.8 0.105 0.96 [0.89; 1.03] 0.218
Type of ACS
 STEMI 10 (66.7%) 75 (49.2%) 0.372 Reference 17 (41.5%) 63 (51.2%) 0.537 Reference
 NSTEMI 5 (33.3%) 72 (47.1%) 0.54 [0.18; 1.58] 0.260 22 (53.7%) 56 (45.5%) 1.31 [0.70; 2.46] 0.405
 UA 0 (0.0%) 6 (3.9%) NA* 0.992 2 (4.9%) 4 (3.3%) 1.28 [0.30; 5.54] 0.741
Coronary angiography
 I. no significant lesions 2 (13.3%) 6 (4.0%) 0.224 Reference 0 (0.0%) 7 (5.7%) 0.061 Reference
(I and II)
 II. single-vessel disease 2 (13.3%) 34 (22.5%) 0.18 [0.02; 1.28] 0.087 5 (12.5%) 30 (24.6%) Reference
(I and II)
 III. multi-vessel disease 11 (73.3%) 111 (73.5%) 0.29 [0.06; 1.32] 0.110 35 (87.5%) 85 (69.7%) 2.62 [1.02; 6.68] 0.044
Treatment
 Conservative therapy 5 (33.3%) 27 (17.6%) 0.246 Reference 8 (19.5%) 22 (17.9%) 0.610 Reference
 PCI 10 (66.7%) 117 (76.5%) 0.49 [0.17; 1.43] 0.193 32 (78.1%) 93 (75.6%) 1.16 [0.53; 2.52] 0.707
 CABG 0 (0%) 9 (5.9%) NA* 0.991 1 (2.4%) 8 (6.5%) 0.43 [0.05; 3.44] 0.427
Treatment
 Conservative therapy 5 (33.3%) 27 (17.7%) 0.166 Reference 8 (19.5%) 22 (17.9%) 0.816 Reference
 PCI or CABG 10 (66.7%) 126 (82.3%) 0.46 [0.16; 1.33] 0.152 33 (80.5%) 101 (82.1%) 1.10 [0.51; 2.39] 0.804
Hypertension 11 (73.3%) 129 (84.3%) 0.281 0.55 [0.17; 1.72] 0.304 37 (90.2%) 101 (82.1%) 0.217 1.84 [0.66; 5.18] 0.245
Diabetes mellitus 5 (33.3%) 54 (35.3%) 0.879 0.92 [0.31; 2.69] 0.877 19 (46.3%) 40 (32.5%) 0.110 1.64 [0.89; 3.02] 0.116
Previous MI 2 (13.3%) 41 (26.8%) 0.359 0.43 [0.10; 1.89] 0.263 16 (39.0%) 29 (23.6%) 0.055 1.78 [0.95; 3.33] 0.073
Previous PCI 2 (13.3%) 41 (26.8%) 0.359 0.44 [0.10; 1.93] 0.275 15 (36.6%) 29 (23.6%) 0.103 1.68 [0.89; 3.17] 0.111
Previous CABG 1 (6.7%) 17 (11.1%) 1.000 0.65 [0.09; 4.96] 0.680 3 (7.3%) 15 (12.2%) 0.566 0.72 [0.22; 2.34] 0.587
CHF with EF ≥ 50% 2 (13.3%) 10 (6.5%) 0.291 2.12 [0.48; 9.40] 0.322 9 (21.9%) 3 (2.4%) < 0.001 4.59 [2.17; 9.74] < 0.001
CHF with EF < 50% 1 (6.7%) 11 (7.2%) 1.000 0.94 [0.12; 7.15] 0.953 6 (14.6%) 6 (4.9%) 0.075 2.36 [0.99; 5.62] 0.052
Previous AF 5 (33.3%) 26 (17.0%) 0.157 2.23 [0.76; 6.55] 0.142 14 (34.1%) 17 (13.8%) 0.004 2.30 [1.21; 4.40] 0.011
Previous CKD 7 (46.7%) 39 (25.5%) 0.125 2.42 [0.88; 6.66] 0.088 18 (43.9%) 27 (21.9%) 0.006 2.31 [1.25; 4.30] 0.008
COPD 2 (13.3%) 15 (9.8%) 0.651 1.41 [0.32; 6.23] 0.654 6 (14.6%) 12 (9.8%) 0.395 1.33 [0.56; 3.16] 0.524
Peripheral artery
disease
2 (13.3%) 18 (11.8%) 0.694 1.18 [0.27; 5.23] 0.828 7 (17.1%) 14 (11.4%) 0.345 1.59 [0.70; 3.58] 0.267
Previous stroke/TIA 3 (20.0%) 18 (11.8%) 0.406 1.81 [0.51; 6.41] 0.395 8 (19.5%) 11 (8.9%) 0.089 2.06 [0.95; 4.46] 0.067
Malignant disease 5 (33.3%) 18 (11.8%) 0.036 3.38 [1.15; 9.89] 0.026 6 (14.6%) 15 (12.2%) 0.686 1.37 [0.58; 3.27] 0.475
Hypercholesterolemia or hyperlipidemia 6 (40.0%) 119 (77.8%) 0.003 0.21 [0.08; 0.60] 0.003 33 (80.5%) 92 (74.8%) 0.458 1.52 [0.70; 3.30] 0.292
Hgb on admission to hospital, g/dL 11.6 ± 1.4 13.3 ± 1.8 < 0.001 0.69 [0.56; 0.85] < 0.001 12.8 ± 2.1 13.5 ± 1.7 0.020 0.84 [0.73; 0.97] 0.021
EF assessed during hospitalization, % 39.1 ± 13.2 48.5 ± 12.3 0.006 0.95 [0.91; 0.99] 0.008 42.3 ± 13.8 49.6 ± 11.4 < 0.001 0.96 [0.94; 0.99] 0.002