Table 3. Clinical events at 12 months follow up in matched groups.
| SIERRA-75 | Control | P | |
| N= 686 | N= 686 | ||
| Data are presented as n (%). BL: bleeding BARC 2-5; MI: myocardial infarction; ST: stent thrombosis; TLR: target lesion revascularization. | |||
| Co-Primary safety endpoints | |||
| Cardiac death/MI/ST | 46 (6.7%) | 56 (8.1%) | 0.29 |
| Bleeding BARC 2-5 | 51 (7.4%) | 70 (10.2%) | 0.04 |
| Primary efficacy endpoint | |||
| Target lesion revascularization | 12 (1.7%) | 18 (2.6%) | 0.25 |
| Secondary endpoints | |||
| All cause death | 50 (7.3%) | 56 (8.2%) | 0.53 |
| Cardiac death | 26 (3.8%) | 30 (4.4%) | 0.57 |
| Myocardial infarction | 25 (3.6%) | 32 (4.6%) | 0.35 |
| Stent thrombosis definite/probable | 10 (1.5%) | 16 (2.3%) | 0.23 |
| All revascularizations | 24 (3.5%) | 32 (4.7%) | 0.26 |
| Stroke | 7 (1%) | 6 (0.9%) | 0.84 |
| Cardiac death/MI/ST/TLR | 53 (7.7%) | 64 (9.3%) | 0.27 |
| Cardiac death/MI/ST/TLR/BL | 98 (14.3%) | 127 (18.5%) | 0.02 |