Figure S2. Clonal distribution and overlap of diabetogenic CD8 T cells.

(A) Venn diagram showing clonal overlap of spleen clones from two experiments. Singlet clones were excluded from this analysis. (A, B) As in (A), but showing all non-singlet clones from each experiment. Clones are defined using CDR3 nucleotide sequences from the TCR α chain only (top left), TCR β chain only (top right), or both chains paired at the single-cell level (bottom). (C) UpSet diagram showing clonal overlap among all combinations of samples. (D) Bar plot showing size and sample origin of clones with at least two constituent cells. Each bar represents one clone, color denotes sample identity. Clone and cell counts shown in the legend are restricted to non-singlet clones.