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. 2022 May 24;9:891958. doi: 10.3389/fmed.2022.891958

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Copyright © 2022 Yin, Li, Li, She, Liu, Chen, Ma, Ma, Huang, Xu, Huang, Zhan and Che.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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(a) In epidermis and dermis, there are abundant pale-staining cytoplasmic, which are flaky, small nests or scattered cells in HE staining, involving both the dermis and skin appendages. Left arrow: Paget cell. Right arrow: infiltrating adenocarcinoma. (b) Positive expression of CK (7) in EMPD section 100×. (c) Negative expression of CK (20) in EMPD section 100×. (d) Negative expression of CD (56) in EMPD section 100×. (e) Negative expression of ChrA in EMPD section 100×. (f) Focal positive expression of synaptophysin in EMPD section 100×.