A, Median PFS time was 8.4 months for patients with driver variations vs 40.1 months in patients without driver variations (log-rank P < .001). B, Median PFS time was 8.4 months for the non–KRAS driver mutation group, 8.0 months for the KRAS driver mutation group, and 40.1 months for the non-driver mutation group (log-rank P = .001). C, Median OS time was 36.2 months for those with driver variations and was not achieved in those without driver variations (log-rank P = .24).