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. 2022 Mar 14;7(6):1229–1240. doi: 10.1016/j.ekir.2022.03.007

Figure 5.

Figure 5

Association between glomerular capillaries and ECM area. Bivariate plots of glomerular capillary area and ECM area in 3 groups (FSGS-scl[+], FSGS-scl[−], and control glomeruli) are shown in (a). For bivariate plots of glomerular capillary/glomerular area ratio and ECM/glomerular area ratio made to avoid the effect of glomerular size, comparisons among the 3 groups (FSGS-scl[+], FSGS-scl[−], and control glomeruli) are shown in (b). Bivariate plots of the glomerular capillary area and ECM area in each FSGS variant are shown in (c). Bivariate plots corrected for glomerular size in each FSGS variant are shown in (d). All graphs are divided into 4 areas by drawing a horizontal or vertical line with the average value of all measured glomeruli. ECM, extracellular matrix; FSGS, focal segmental glomerular sclerosis; FSGS-scl(−), glomeruli without sclerotic lesions in FSGS; FSGS-scl(+), glomeruli with sclerotic lesions in FSGS; n.s., no significance; NOS, not otherwise specified; r, correlation coefficient, Spearman's rank correlation coefficient.