Table 2.
Simulation parameter specifications: match failure rates are considered in the simulations
cPRA level | Match failure rate |
||
---|---|---|---|
BLa | Living donor transplant (BL + 0.1) | DD-CIK transplantb (BL + 0.2) | |
75–100 | 0.5 | 0.6 | 0.7 |
50–74 | 0.35 | 0.45 | 0.55 |
25–49 | 0.2 | 0.3 | 0.4 |
0–24 | 0.05 | 0.15 | 0.25 |
BL, baseline; cPRA, calculated panel-reactive antibody; DD-CIK, deceased donor-chain–initiating kidney.
Include a baseline probability or rate that depends on cPRA plus an additional 0.1 for living donor transplant offers or 0.2 for DD-CIK transplant offers.
Baseline values are taken from Ashalgi et al.9
Exception: BL + 0.5 for a blood type A candidate with cPRA <75% and a blood type O donor. This exception reflects the fact that such candidates may be unwilling to accept a deceased donor when a living donor exchange will likely eventually be open to them.