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Injections of sgRNA/Cas9 plasmid targeting the Avpr1a gene into hamster embryos. (A) Alignments of various indels produced by CRISPR-Cas9 editing. Only C1 FOUNDER was able to produce offspring resulting in generations F1 and F2. (B) Predicted proteins produced by indels. (C) F (Top of each photo) and M (Bottom of each photo) Avpr1a KOs (Right side of each photo) exhibit no obvious physical differences compared to WT (Left side of each photo).
