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. 2022 May 4;21(6):1449–1466. doi: 10.1021/acs.jproteome.2c00043

Figure 4.

Figure 4

Summary of the types of N-glycan identified in the healthy adult rat spinal cord. (A) All of the major classes of N-glycan can be found in the spinal cord, oligomannose, hybrid, and branched. Branched glycans also occur with a bisecting GlcNAc β(1–4) linked to the central mannose. Some more unusual features such as acetylated sialic acids, sulfate groups, and α-linked galactose can also be found on complex or hybrid glycans. (B) Number of branches on complex glycans, some also feature a bisecting GlcNAc β(1–4) linked to the central mannose. A2 and A3 structures are most common. (C) Charge abundance as calculated using WAX-HPLC. (D) Extent of branch elongation with galactose on each class of N-glycan. (E) Proportion of total glycans decorated with both core and outer-arm fucose. (F) Distribution of fucosylation across the main N-glycan classes.