Table 4.
Standard two dimensional echocardiographic measurements and Z scores at baseline and at the end of the study
| Characteristic | MeanBaseline (B) | Group 1 (N: 17) (1) | Group 2 (N: 15) (2) | P-value 1,2 | 1,B | 2,B |
|---|---|---|---|---|---|---|
| LVIDd (mm) LVIDd/BSA LVIDd (Z score) |
40.4 ± 4.6 40.2 ± 8.4 - 0.03 ± 0.9 |
40.9± 12.3 38.6 ± 8.2 0.46 ± 0.9 |
43.8 ± 7.8 46.2±16.6 0.91 ± 1.4 |
1.00 0.35 1.00 |
1.00 0.56 1.00 |
0.37 1.00 0.62 |
| LVISd (mm) LVISd/BSA LVISd(Z score) |
25.1 ± 4.8 25.0 ± 6.1 0.04 ± 0.9 |
27.2 ± 4.8 23.9 ± 5.6 0.2 ± 1.0 |
28 ± 7.0 28.9±10.5 0.91 ± 1.4 |
1.00 0.37 0.21 |
0.71 0.61 0.21 |
0.55 1.00 1.00 |
| IVSd (mm) IVSd/BSA IVSd (Z score) |
5.6 ± 1.3 5.5 ± 1.6 -0.5 ± 1.1 |
7.0 ± 1.5 6.2 ± 1.9 0.4 ± 0.9 |
6.1± 2.5 5.9 ± 1.8 0.0026±1.3 |
0.77 1.00 1.00 |
1.00 1.00 1.00 |
0.07 0.78 0.07 |
| LVPWd (mm) LVPWd/BSA LVPWd(Zscore) |
5.0 ± 0.9 4.9 ± 0.9 -0.6 ± 0.6 |
5.9 ± 1.3 5.2 ± 1.2 0.01 ± 1.0 |
5.4 ± 2.2 5.4 ± 2.2 0.1 ± 1.6 |
1.00 1.00 1.00 |
1.00 1.00 0.36 |
0.24 1.00 0.34 |
| EF (%) | 68.0 ± 7.3 | 68.0 ± 7.5 | 69 ± 8.3 | 1.00 | 1.00 | 1.00 |
| SF (%) | 37.9 ± 6.1 | 38.0 ± 5.8 | 38 ± 7 | 1.00 | 1.00 | 1.00 |
| AoAn(mm) AoAn/BSA AoAn(Z score) |
16.3 ± 2.1 16.0 ± 2.7 0.5 ± 0.7 |
17.6 ± 1.9 15.6 ± 3.1 0.8 ± 0.8 |
17 ± 3.1 17.7 ± 5.9 1.1 ± 1.2 |
1.00 0.64 1.00 |
1.00 0.86 0.26 |
0.34 1.00 0.82 |
| Sinvals (mm) Sinvals/BSA Sinvals(Zscore) |
20.4 ± 2.9 20.0 ± 3.1 -0.4 ± 0.7 |
21.9 ± 2.7 19.3 ± 3.5 -0.2 ± 0.7 |
22.8 ± 5.2 23.4 ± 7.2 0.73 ± 1.2 |
1.00 0.13 0.04 |
0.34 0.22 0.06 |
0.68 1.00 1.00 |
| Sintubj (mm) Sintubj/BSA Sintubj(Z score) |
17.9 ± 2.3 17.6 ± 3.0 0.4 ± 0.6 |
19.8 ± 2.6 17.4 ± 3.2 0.8 ± 0.7 |
19.6 ± 3.9 20.5 ± 7.6 1.2 ± 1.1 |
1.00 0.35 0.94 |
0.44 0.36 0.07 |
0.21 1.00 0.32 |
| AscAo (mm) AscAo/BSA AscAo(Z score) |
18.1 ± 2.1 17.8 ± 3.1 - 0.2 ± 0.8 |
21.0 ± 3.1 18.4 ± 3.4 1.2 ± 1.7 |
20.3 ± 4.8 21.1 ± 7.7 0.89 ± 1.9 |
1.00 0.57 1.00 |
0.31 0.27 0.18 |
0.04 1.00 0.02 |
| PVAn (mm) PVAn/BSA PVAn (Z score) |
17.2 ± 3.2 16.9 ± 3.4 -0.7 ± 0.9 |
19.5 ± 3.4 17.1 ± 3.7 - 0.3 ± 1.0 |
18.8 ± 4.3 19.9 ± 8.8 0.02 ± 1.5 |
1.00 0.70 0.79 |
0.94 0.53 1.00 |
0.27 1.00 0.38 |
| MPA (mm) MPA/BSA MPA(Z score) |
16.3 ± 2.1 16.3 ± 3.8 -1.1 ± 0.8 |
17.8 ± 3.2 15.7 ± 3.7 - 0.8 ± 1.0 |
19.5 ± 4.2 21.86±11.2 0.01 ± 0.95 |
0.63 0.08 0.15 |
0.04 0.10 0.07 |
0.51 1.00 1.00 |
| LPA (mm) LPA/BSA LPA(Z score) |
11.3 ± 1.5 11.6 ± 3.7 0.4 ± 1.2 |
13.3 ± 1.5 12.0 ± 3.5 1.3 ± 0.9 |
16.9 ± 4.7 17.7 ± 7 2.9 ± 1.3 |
0.01
0.02 0.01 |
0.08 0.06 0.1 |
0.09 1.00 0.15 |
| RPA (mm) RPA/BSA RPA (Z score) |
11.1 ± 1.4 11.2 ± 3.4 - 0.4 ± 1.0 |
14.0 ± 1.8 12.5 ± 3.4 0.5 ± 0.9 |
15.4 ± 2.1 16.5 ± 6.9 1.7 ± 1.1 |
0.20 0.12 0.06 |
0.09 0.08 0.2 |
0.01 1.00 0.02 |
| TVmax | 17.7±3.0 (16) | 18.4±2.1 (10) | 18 ± 2.9 | 1.00 | 1.00 | 1.00 |
| LA/AO | 1.5 ± 0.2 | 1.6 ± 0.2 | 1.8 ± 0.26 | 0.29 | 0.23 | 0.38 |
| IVRT, ms | 66.9±9.6 (17) | 70.5±13.0 (13) | 77.1 ± 20.4 | 0.84 | 0.26 | 1.00 |
| IVRT, corrected | 80.7±11.7 (11) | 80.7±17.5 (9) | 91.9 ± 23.4 | 0.45 | 0.17 | 1.00 |
| CI | 4.1±0.60 (9) | 4.6 ± 1.0 | 4.8±1.2 (7) | 1.00 | 0.98 | 0.71 |
LVIDd, left ventricular end diastolic dimension; LVISd, Left ventricular end systolic dimension; IVSd, interventricular septal dimension in diastole; LVPWd, left ventricular posterior wall dimension in diastole; EF, ejection fraction; SF, shortening fraction; AoAn, aortic valve annulus; Sinvals, sinus of valsalva; Sintubj, sinotubular junction; AscAo, ascending aorta; PVAn, pulmonary valve annulus; MPA, main pulmonary artery; LPA, left pulmonary artery; RPA, right pulmonary artery; TVmax, tricuspid valve regurgitation maximum peak velocity; LA/Ao, Left atrium aortic dimension ratio by M-mode; IVRT, Isovolumic relaxation time; CI, Cardiac index.
* Corrected for heart rate. P value is significant ≤ 0.05; significant values are highlighted in bald.