Table 5.
Standard and Tissue Doppler Echocardiographic measurement at baseline and at the end of the study
| Characteristic | Group 1 (end of study) N=17 | Group 2 (end of study) N=15 | Mean Baseline (B) N=32 | P-value 1 vs.2 | P-value 2,B | P-value 1,B |
|---|---|---|---|---|---|---|
| Mitral Valve | ||||||
| Em, cm/s | 114.2 ± 11.9 | 110 ± 17.8 | 103.3 ±19.0 | 1.00 | 0.96 | 0.25 |
| Am, cm/s | 55.3 ± 13.4 | 72 ± 19.7 | 52.2 ± 11.4 | 0.03 | 0.01 | 1.00 |
| Em/Am ratio | 2.2 ± 0.5 | 1.6 ± 0.39 | 2.04 ± 0.5 | 0.03 | 0.07 | 1.00 |
| Amd, ms | 122.1 ± 30.6 | 131.3 ± 37.9 | 110.2± 23.0 | 1.00 | 0.29 | 0.81 |
| DTm, ms | 165.8 ± 25.4 | 146.8 ± 27.8 | 141.8± 22.9 | 0.29 | 1.00 | 0.04 |
| DTm, corrected for heart rate | 194.1 ± 37.8 | 173.2 ± 25.5 | 159. ± 28.6 | 0.38 | 1.00 | 0.05 |
| S′m, cm/s | 10.1 ± 1.6 | 10.25 ± 2.9 | 9.7 ± 1.7 | 1.00 | 1.00 | 1.00 |
| E′m, cm/s | 20.5 ± 2.8 | 19.8 ± 2.8 | 19.8 ± 3.3 | 1.00 | 1.00 | 1.00 |
| A′m, cm/s | 6.9 ± 1.6 | 8.5 ± 2.1 | 7.0 ± 1.02 | 0.07 | 0.07 | 1.00 |
| E′m/A′m | 2.9 ± 0.82 | 2.5 ± 0.69 | 2.89 ± 0.69 | 0.75 | 0.75 | 1.00 |
| Septum | ||||||
| S′s, cm/s | 8.9 ± 1.4 | 8.9 ± 1.8 | 8.4 ± 1.1 | 1.00 | 1.00 | 0.89 |
| E′s, cm/s | 14.5 ± 1.9 | 13.4 ± 1.5 | 15.5 ± 2.6 | 0.83 | 0.08 | 0.59 |
| A′s, cm/s | 7.2 ± 1.5 | 7.6 ± 1.8 | 6.5 ± 1.1 | 1.00 | 0.21 | 0.64 |
| E′s/A′s | 2.1 ± 0.5 | 1.9 ± 0.71 | 2.4 ± 0.5 | 1.00 | 0.08 | 0.32 |
| Em/E′m | 5.4 ± 1.4 | 5.9 ± 1.8 | 5.3 ± 1.1 | 1.00 | 0.35 | 0.48 |
| Tricuspid valve | ||||||
| S′t, cm/s | 14.8 ± 2.5(12) | 13.25 ± 2.5 | 13.2 ± 2.1 | 0.49 | 1.00 | 0.25 |
| E′t, cm/s | 15.8 ± 1.8(12) | 16.6 ± 2.8 | 16.1 ± 1.9 | 1.00 | 1.00 | 1.00 |
| A′t cm/s, | 11.8 ± 3.2 | 12 ± 3.6 | 10.2 ± 2.1 | 1.00 | 0.41 | 0.37 |
| E′t/A′t | 1.4 ± 0.48 | 1.5 ± 0.52 | 1.7 ± 0.47 | 1.00 | 1.00 | 0.69 |
| Pulmonary vein | ||||||
| Spv, cm/s | 56.4 ± 7.3 | 57.7 ± 12.5 | 48.8 ± 9.0 | 1.00 | 0.11 | 0.09 |
| Dpv, cm/s | 64.2 ± 9.3 | 54.6 ± 6.3 | 60.2 ± 12.2 | 0.173 | 0.69 | 0.92 |
| Apv, cm/s | 22.8 ± 7.9 | 18.9 ± 5.0 | 19.6 ± 5.0 | 0.56 | 1.00 | 0.50 |
| Apvd, ms | 83.0 ± 17.8 | 80.7 ± 20.8 | 85.4 ± 18.2 | 1.00 | 1.00 | 1.00 |
| Spv/Dpv | 0.9 ± 0.1 | 1.1 ± 0.27 | 0.8 ± 0.2 | 0.09 | 0.01 | 1.00 |
| Amd/Apvd | 1.5 ± 0.3 | 2.2 ± 0.95 | 1.3 ± 0.4 | 0.001 | 0.01 | 1.00 |
Em, peak early mitral valve flow velocity; Am, peak late mitral valve flow velocity; Em/Am, Em/Am ratio, Amd, Am duration; DTm, deceleration time of Em wave; S′m, peak systolic velocity of mitral valve; E′m, peak early diastolic velocity of the mitral valve; A′m, peak late diastolic velocity of mitral valve; E′m/A′m, E′m/A′m ratio; S′s, peak systolic velocity of the septum; E′s, peak early diastolic velocity of the septum; A′s, peak late diastolic velocity of the septum; E′s/A′s, E′s/A′s ratio; S′t, peak systolic velocity of the tricuspid valve; E′t, peak early diastolic velocity of the tricuspid valve; A′t, peak late diastolic velocity of the tricuspid valve; E′t/A′t, E′t/A′t ratio; Spv, peak systolic velocity of the pulmonary vein; Dpv, peak diastolic velocity of the pulmonary vein; Apv, peak A wave reversal in the pulmonary vein; Apvd, peak A wave reversal duration in the pulmonary vein; Amd/Apvd, Amd/ Apvd ratio.
P value is significant ≤ 0.05; significant values are highlighted in bald.