Table 3.
ROC analyses of CXCL10 for diagnosis of CTEPH
| ROC analysis of CXCL10 for diagnosis of CTEPH | AUC (95% CI) | Cutoff value (pg/ml) | Sensitivity (%) | Specificity (%) | ||
|---|---|---|---|---|---|---|
| CXCL10 | 0.80 (0.69–0.89) | >18.6 | 81.4 | 71.4 | ||
| Multiple logistic regression model and ROC analysis | OR (95% CI) | p | AUC (95% CI) | Cutoff value (probability) | Sensitivity (%) | Specificity (%) |
| CXCL10 (pg/ml) | 1.092 | <0.0001 | 0.83 (0.72–0.91) | > 0.452 | 86.0 | 67.9 |
| (1.042–1.144) | ||||||
| Age (year) | 1.015 | 0.65 | ||||
| (0.952–1.083) | ||||||
| Sex (female) | 1.481 | 0.55 | ||||
| (0.413–5.313) | ||||||
Abbreviations: AUC, area under the curve; CI, confidence interval; CTEPH, chronic thromboembolic pulmonary hypertension; CXCL10, chemokine (C‐X‐C motif) ligand 10; OR, odds ratio; ROC, receiver operating characteristic curve.