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. 2022 Jun 7;20:205. doi: 10.1186/s12916-022-02375-4

Table 4.

Frequency of personal and self-reported family historya of syndrome-related phenotypes pre-result disclosure in participants identified via MyCode

Gene Personal history of ETS-associated feature(s) Self-reported family history of ETS-associated feature(s) Met genetics referral criteria

All

n=65

8%

(n=5/65)

25%

(n=16/65)

11%

(n=7/65)

MEN1

n=2

0%

(n=0/2)

100%

(n=2/2)

0%

(n=0/2)

RET

n=31

0%

(n=0/31)

26%

(n=8/31)

10%

(n=3/31)

VHL

n=1

0%

(n=0/1)

0%

(n=0/1)

0%

(n=0/1)

SDHx

n=31

16%

(n=5/31)

19%

(n=6/31)

13%

(n=4/31)

SDHAF2

n=2

0%

(n=0/2)

50%

(n=1/2)

0%

(n=0/2)

SDHB

n=15

27%

(n=4/15)

27%

(n=4/15)

20%

(n=3/15)

SDHC

n=9

0%

(n=0/9)

11%

(n=1/9)

0%

(n=0/9)

SDHD

n=5

20%

(n=1/5)

0%

(n=0/5)

20%

(n=1/5)

aPersonal and self-reported family history of syndrome-related findings are noted in Table 1