Table 3.

Univariate and multivariate Cox regression analyses of overall survival in hypopharyngeal carcinoma patients

Variable	Univariate analyses			Multivariate analyses
	HR	95%CI	P*	HR	95%CI	P*
Age	1.738	0.791–3.576	0.341
Smoking	1.797	0.994–5.260	1.109
Gender	0.037	0.014–12.581	0.803
Pathological stage	1.429	0.056–3.292	0.094
Lymphatic metastasis	3.155	1.782–6.191	0.027	2.409	0.975–4.722	0.038
Pathological differentiation	1.126	0.603–2.797	0.062
Expression of RAF1	1.894	1.069–4.467	0.033	1.153	0.776–3.291	0.048
Extracapsular spread	4.512	2.607–7.335	0.045	3.731	2.240–5.699	0.070

^*P values are from Cox analyses were statistically significant when < 0.05