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. 2022 Jun 1;42(22):4435–4448. doi: 10.1523/JNEUROSCI.2246-21.2022

Figure 7.

Figure 7.

Inhibiting S1 influences the sensory-evoked response of S2 single whisker deflection. A, Left, Average of wS2 and wS1 evoked MUA response in L2-3, L4, and L5 of P14-P16 age group mice (n = 9) in the control condition (black) and TTX injection in wS1 (orange). Inset, The detailed paired t test comparison of mean firing rate between control and TTX injection conditions using 10 ms bins during the period of 0-200 ms after the onset of whisker stimulation. Right, Average of wS2 and wS1 evoked MUA response in L2-3, L4, and L5 of P25-P56 age group mice (n = 5) in the control condition (black) and TTX injection in S1 (orange). B, The mean firing rate of wS2 and wS1 evoked response in L2-3, L4, and L5 during the period of 0-100 and 100-1000 ms after the onset of the whisker stimulation of P14-P16 and P25-P56 age groups in the control (black) and TTX injection in S1 (orange) condition. Statistical comparison was performed between control and TTX conditions: *p < 0.05; **p < 0.01; ***p < 0.001; paired t test. All the values of data points, the mean and SEM of each group, and statistical p and t values are in Extended Data Figure 7-1.