TABLE 4.

Main effect of gender on absolute and relative changes in body weight and blood biochemistry among treated mice.

Parameters	Female (n)	Male (n)	P-value
	Mean ± SD
Body weight (BW, g)
ΔBW = T6-T4	−4.92 ± 3.86(54)	−6.72 ± 3.08(60)	0.0067**
CBW = ΔBW/T4	−0.14 ± 0.10(54)	−0.15 ± 0.06(60)	0.5139
Total cholesterol (TC, mg/dL)
ΔTC = T6-T4	−95.74 ± 39.90(53)	−133.86 ± 54.25(59)	< 0.0001****
CTC = ΔTC/T4	−0.52 ± 0.13(53)	−0.55 ± 0.14(59)	0.2441
High-density lipoprotein cholesterol (HDL, mg/dL)
ΔHDL = T6-T4	−55.42 ± 17.56(53)	−66.54 ± 23.69(59)	0.0061**
CHDL = ΔHDL/T4	−0.53 ± 0.10(53)	−0.49 ± 0.16(59)	0.1203
Blood glucose (Glu, mg/dL)
ΔGlu = T6-T4	40.62 ± 59.83(53)	−2.71 ± 83.20(59)	0.0022**
CGlu = ΔGlu/T4	0.28 ± 0.40(53)	0.04 ± 0.34(59)	0.0008***
Triglycerides (TG, mg/dL)
ΔTG = T6-T4	−3.98 ± 26.58(53)	−0.88 ± 27.94(59)	0.5498
CTG = ΔTG/T4	−0.04 ± 0.58(53)	−0.07 ± 0.51(59)	0.2879

SD, standard deviation; n, number of animals; Δ, absolute change; C, relative change. P-values were calculated using the unpaired two-tailed Student’s t-test for absolute as well as relative changes. Asterisks indicate statistical significance.